The crossover sports sim was one of four Mario-themed titles in the top ten, with Mario Kart Wii and Mario Party 9 holding onto top-six slots.
With no new entries, New Super Mario Bros Wii clawed its way back into the top ten, sitting in ninth ahead of 505 Games's Zumba Fitness.
The top ten in full:
1. (1) Mario & Sonic at the London 2012 Olympic Games (Sega)
2. (2) LEGO Batman 2: DC Super Heroes (Warner Bros Interactive)
3. (4) Mario Kart Wii (Nintendo)
4. (6) Zumba Fitness 2 (505 Games)
5. (5) Skylanders: Spyro's Adventure (Activision)
6. (4) Mario Party 9 (Nintendo)
7. (7) Wii Party (Nintendo)
8. (11) Quiz Party (CK Games)
9. (12) New Super Mario Bros Wii (Nintendo)
10. (8) Zumba Fitness (505 Games)
Leisure software charts compiled by Chart Track, (C) 2012 UKIE Ltd.
Watch The Wanted play Mario & Sonic at the London 2012 Olympic Games below: