The gameplay trailer provides some backstory of the zombie epidemic, along with tips for surviving the infected streets of London.
Announced at E3, ZombiU is a survival horror game where players must make their way through a zombie-infected London to reach the safe zone.
Dying will cause players to take control of a new character, and they must defeat the zombie of their previous life to recover equipment.
In addition to the single player campaign, multiplayer will put one player in control of the zombie horde against a human opponent fighting for control of the map.
ZombiU will be available exclusively on Wii U when the system launches this holiday season.
Watch the announcement trailer for ZombiU below: