The classic adventure game will arrive on iOS devices from September 27.
Set on the Orient Express in 1914, players take on the role of Robert Cath, an American doctor who gets caught in a twisting plot aboard the train.
For the iOS release, it will receive enhancements to make the action easier to control with a touchscreen, while keeping the original art and voice acting intact.
The game was originally released in 1997, developed by Prince of Persia creator Jordan Mechner.
Watch the trailer for The Last Express below: