The uncompromising role-playing game is up for 'Best RPG', 'Top Gaming Moment' and 'Ultimate Game of the Year'.
Describing Dark Souls as difficult and peculiar, the game's director and designer Hidetaka Miyazaki was keen to thank fans for their support.
"I am so glad to hear that Dark Souls was nominated for these awards," Miyazaki revealed.
"It may be strange to hear from me but Dark Souls is extremely difficult and has a peculiar in-game universe, so it is not anything like games that are easy to pick up and play.
"However, Dark Souls could achieve these honourable awards thanks to all who played it. As the director of Dark Souls and on behalf of FromSoftware, I am grateful to all of you.
"Keeping the fans' voices and this nomination in mind, I promise to all our fans to create more enjoyable and valuable games."
Voting for the awards, which will be entering their 30th year, is open from now until October 22.
The results will be announced on October 26 at an awards ceremony in London hosted by comedian Ed Byrne, and the event will also offer exclusive reveals of new titles.
Returning categories include 'Best Handheld Game', 'One To Watch' and 'Ultimate Game of the Year'.
Meanwhile, this year's 'Best Action Adventure Game' is being sponsored by Digital Spy.
> Read the full list of Golden Joystick Awards 2012 nominees here
> Cast your vote in the 30th Golden Joystick Awards
Watch a trailer for Dark Souls below: