In a post on Epic's blog, studio founder Tim Sweeney said his farewell to the iconic designer.
"In 20 wonderful years with Epic, Cliff Bleszinski has grown into a true design luminary, and his contributions to the Unreal and Gears series have helped shape the game industry into what it is today," Sweeney said.
"Cliff leaves Epic with our gratitude for his many contributions, and our wishes for continued success in the next chapter of his life!"
Bleszinski gave his own farewell statement on the blog, saying: "I've been doing this since I was a teenager, and outside of my sabbatical last year, I have been going non-stop. I literally grew up in this business, as Mike likes to say. And now that I'm grown up, it's time for a much needed break.
"I will miss the projects, the playtests, the debates, and most importantly, the people. Epic only hires the best of the best, and it has been a joy working with each and every one of you on a daily basis, whether you were hired weeks ago or decades ago.
"I have been fortunate enough to collaborate with a variety of disciplines, from code to art to marketing and PR - it's been one big, rewarding learning experience. I'm confident that each project that is being built, whether at Epic, Chair, PCF, or Impossible will be top notch and will please gamers and critics alike."
Bleszinski has been a designer for Epic Games for nearly 20 years, shaping franchises such as Jazz Jackrabbit, Unreal, Unreal Tournament and Gears of War.
He was most recently working on Epic's upcoming co-op survival game Fortnite and Gears of War: Judgement.
Cliff Bleszinski's future plans are unknown at this time, though his personal statement appears to indicate he may be stepping away from the video game industry entirely, at least temporarily.
Screenshot gallery - images of Fortnite below:
Copyright: Epic Games