Attendees will have the chance to try out the gaming giant's new console upon its release in the London show's Game Zone.
New Super Mario Bros Wii U, Assassins Creed III, FIFA Soccer 13 and Batman: Arkham City: Armored Edition are among the titles from the Wii U launch line-up that attendees will be able to test.
Electronic Arts and Microsoft will also attend The Gadget Show Christmas to offer members of the public the opportunity to go hands-on with their Christmas line-up.
Retailer Game will also be on hand with festive discounts on games, accessories and consoles, as will PC hardware firm Overclockers. A dedicated Gaming Stage will host mass play sessions and provide challenges for novices and experts alike.
"With more than 150 tech companies showcasing thousands of the best gadget gifts, games and toys in the UK, Gadget Show Christmas is three days of tech heaven for all the family," said event director Matt Hodgins.
"It's a unique opportunity to get hands-on with the best tech around while also stocking up on all the gadgets which are setting Christmas lists alight."
The Gadget Show Christmas takes place at ExCeL in London between Friday, November 30 and Sunday, December 2.
Watch Digital Spy go hands-on with the Wii U below: