Releasing exclusively for the Nintendo 3DS, the upcoming titles will launch across all regions in October.
Announced during a Direct presentation by Nintendo president Satoru Iwata, the games will feature brand new Pokémon such as Chespin, Fennekin and Froakie, as well as a new female adventurer.
Taking place in a fully realised 3D world, Iwata suggested that the titles, which are in development at Game Freaks, will take advantage of a number of the handheld's unique features.
The announcement trailer (above), meanwhile, teases the game's new Legendary Pokémon and bonding system.
"We brought Pokémon into an entirely new dimension and we're incredibly excited to bring Pokémon X and Pokémon Y to fans," explained Game Freaks director Junichi Masuda.
"The stunning visuals, a completely redesigned environment, game scenario, music, and communication features will bring smiles to the faces of video game players around the world," he added.
The launch of Pokémon X and Y will also be accompanied by new toys, animations and trading cards.
Pokémon Black Version 2 and Pokémon White Version 2 released last year on Nintendo DS, marking the first direct sequels in the long-running series.
The release was accompanied by a number of 3DS apps, as well as an official Pokédex app for iOS devices.
> Digital Spy's review of 'Pokemon White Version 2': Evolution, not revolution