The ability to play the 3DS port away from the television screen is one of a number of unique features exclusive to the Wii U version, according to Official Nintendo Magazine (via Nintendo Insider).
Copyright: CapcomThe GamePad will also be used to make inventory changes and display 3D maps. Wii U Pro-controller support is also included.
"There's a joke going around in Japan at the moment about using Off TV Play to play your Wii U games on the Bullet Train, as long as you get on of the seats with a power outlet, so we wanted to make sure Bullet Train play was possible with Revelations," producer Tsukasa Takenaka explained.
"I wouldn't want to be so presumptuous as to say that everyone will enjoy one version more than another, but there are definitely features in the Nintendo Wii U version that are not found on other consoles," he added.
Announced last month, Resident Evil: Revelations will feature improved visuals and enhanced lighting effects, as well as a new enemy type, extra difficulty level and improvements to the Raid mode.
The online co-operative Raid mode adds new weapons, skill sets and extra playable characters such as Hunk.
The game also takes advantage of Residentevil.net, giving players the opportunity to register for Revelations-themed content.
Resident Evil: Revelations will be available at retail on PS3, Xbox 360, Wii U and PC from May 21 in North America and May 24 in Europe.
A downloadable version will also be available the same day on PS3 and PC, with Xbox 360 and Wii U versions to follow.
> Read Digital Spy's 'Resident Evil: Revelations' review
Watch a trailer for Resident Evil Revelations below: