The actor will reprise his role as Green Arrow in NetherRealm Studios' DC Comics-inspired brawler and have an alternate character skin based on his appearance in the show, reports TV Guide.
Announced last year, Injustice: Gods Among Us is said to have a deep, original story, taking place in "a world where the lines between good and evil are blurred".
It features a growing list of heroes and villains from the DC Universe, including Batman, Harley Quinn, Superman, The Flash, Wonder Woman, Catwoman, Solomon Grundy, Nightwing, Cyborg, Green Arrow, Green Lantern, Bane, Deathstroke, Lex Luthor and The Joker.
Mortal Kombat. In 2008, the team also created Mortal Kombat vs DC Universe as Midway Games.
The developers have dropped the traditional three-round fighting system, opting instead for a "more cinematic" single-round system.
Injustice: Gods Among Us will be available on Xbox 360, PlayStation 3 and Wii U on April 16 in North America and April 19 in Europe.
A Collector's Edition will be available for the Xbox 360 and PS3 versions, offering a 25cm statue featuring Batman and Wonder Woman, unique steelbook packaging, an Injustice comic book, and exclusive skins based on The New 52's designs for Batman, Superman and Wonder Woman.
Watch a gameplay trailer for Injustice: Gods Among Us below: