The division's new slate of projects includes The End, a platform game due to launch in April 2011 that will help teenagers explore themes of death, belief and science.
Another project is Walking City - developed by new independent studio Big Robot - which will task players with handling strategic management of a modern urban metropolis.
Alternatively, Footfall will task predominantly female players with running a start-up shoe shop and turning it into a multi-chain empire.
Education will also release real-world financial game International Racing Squirrels, as well as healthy-eating challenge title Yes Chef!, ethical fashion game Closet Swap and tower defence-style online game Sweatshop, created by Littleloud.
Despite the recent closure of Channel 4's digital investment unit 4iP, the Education division has seen its 2011 budget guaranteed to match the 2010 level. An additional £1m has also been earmarked to create content aimed at children aged between 10 and 14.
Initial projects include avatar-based application Who Am I, which will help young people explore their identity and Truth Specs (working title), created by the Somethin' Else agency as an extension of its successful Super Me campaign.
"Channel 4 Education is utterly committed to providing engaging, exciting material for our target audience, now extended to include 10-14 year olds," said Alice Taylor, Channel 4 Education commissioning editor.
"Covering a fantastic range of formats and platforms, the projects are varied and fun whilst still tackling useful and important subject matter.
"As usual we aim to represent teens - and now tweens - in their best light, and to continue to find new talent and recruit UK independents in the drive to provide public service content of the very highest quality."
In the next few weeks Channel 4 Education will also launch a new batch of online videos in the Science Of… series, hosted by Derren Brown. In the Science Of Attraction, Brown will unveil the science behind what makes us appeal to others.
Also this autumn, the division will launch browser-based media literacy game Cover Girl and announce the latest campaigner to sign up to Battlefront.
Click here to read our interview with Taylor, in which she discusses sexual health shooters, closed platforms and why there aren't more games about love.