From New Year's Day, sponsorship for Nikon's Coolpix compact camera range will appear with the soap opera on Channel 4 and E4, running for 12 months.
Nikon previously sponsored Hollyoaks from May to September this year, before Phones 4 U took over to the end of December.
The new sponsorship campaign will run on weekday editions of the soap opera, along with the Saturday omnibus. It will consist of a range of 10-second idents conveying "the emotions and fun of taking pictures with the Coolpix cameras".
Jeremy Gilbert, group marketing manager at Nikon UK, said: "Nikon's sponsorship of Hollyoaks in 2010 proved to be very successful and undoubtedly contributed to a significant rise in market share for our Coolpix products.
"Hollyoaks continues to provide Nikon with access to a young, trendy audience to whom we are able to communicate the strengths of the Coolpix range. We look forward to promoting our key Coolpix products throughout the campaign."