Nicholson will become an executive producer, while Evans will head up development, both reporting to ITVS Factual (North) & Shiver creative director Alexander Gardiner.
Evans will lead development for the whole Factual (North) & Shiver division, overseeing the production of a slate of factual programmes in Manchester and London. She and Nicholson will both be based in Manchester and officially start next month.
"We are very proud of the number and range of programmes which we develop and produce in Manchester; our slate encompasses a wide breadth of ideas from Strictly Kosher to Little England," said Gardiner.
"These latest appointments are a fantastic reflection of our growth in the region and I'm delighted to be welcoming both Andrew and Sally to ITVS Factual (North) & Shiver. Both bring to the team a huge breadth of experience in factual programmes, which will be invaluable in continuing to grow our business in the region."
Evans has previously worked for ITV Studios in a freelance capacity as head of the Manchester development unit, helping to gain commissions for new formats such as daytime series May the Best House Win. Prior to that, she was a producer on various BBC shows, including Street Doctor, Bank of Mum & Dad, and Mastermind.
Nicholson joins ITV Studios from the BBC, where he acted as an executive producer on programmes such as BBC Two's Antiques Master, and Beyond Walford on BBC Three. Prior to this, he worked at Shine Group on shows such as Band for Britain for BBC Two and Banged Up on Channel 5.
"This is a fantastic opportunity to join a hugely talented team committed to making great television in the North," said Nicholson.
"The department is going from strength to strength and I'm looking forward to playing a part in their ongoing success story."
Evans added: "I've thoroughly enjoyed working within this rapidly expanding department at ITV and I'm delighted that I'll continue to be part of such a creative team who have the talent and ambition to carry on growing at a key moment in time for television production in the North."
Current shows in production at ITVS Factual (North) & Shiver include Chatsworth, a documentary for the BBC, as well as May The Best House Win and Someone's Daughter, Someone's Son for ITV1.