Today (September 12) saw the publication of the report from the Hillsborough Independent Panel, which, consistent with the findings of Lord Justice Taylor's earlier report, found that police and emergency services made "strenuous attempts" to deflect the blame for the deaths of 96 Liverpool fans at the FA Cup semi-final on April 15, 1989 on to innocent fans.
Four days after the disaster, a front-page story in The Sun under banner headline 'The Truth' claimed that fans "picked pockets of victims", "urinated on the brave cops" and "beat up PCs giving the kiss of life".
Speaking on publication of the report, Prime Minister David Cameron said that then-editor MacKenzie had to "face up to his own responsibilities" regarding the coverage.
"Today I offer my profuse apologies to the people of Liverpool for that headline," MacKenzie said in a statement.
"I too was totally misled. 23 years ago I was handed a piece of copy from a reputable news agency in Sheffield in which a senior police officer and a senior local MP were making serious allegations against fans in the stadium.
"I had absolutely no reason to believe that these authority figures would lie and deceive over such a disaster."
He continued: "As the Prime Minister has made clear these allegations were wholly untrue and were part of a concerted plot by police officers to discredit the supporters thereby shifting the blame for the tragedy from themselves.
"It has taken more than two decades, 400,000 documents and a two-year inquiry to discover to my horror that it would have been far more accurate had I written the headline 'The Lies rather than The Truth'. I published in good faith and I am sorry that it was so wrong."
Trevor Hicks, Hillsborough justice campaigner and father of two daughters who died in the tragedy, said that MacKenzie's apology was "too little, too late", adding: "The man is low-life."
Today's report found that 41 out of the 96 who died "had the potential to be saved", beyond the 3.15pm timeframe set by the original inquest.
It also found that 164 police statements had been "significantly amended", with 116 negative comments about police leadership removed.
Blood samples of victims was taken by the coroner and criminal records searched by police in a bid to damage the reputation of the victims.
Last week, journalist Harry Arnold said that he had written The Sun report of April 19 in a "fair and balanced way" and that MacKenzie penned 'The Truth' headline.
During an after-dinner speech to Mincoffs Solicitors LLP on November 30, 2006, MacKenzie was alleged to have said he stood by the original report.
"All I did wrong there was tell the truth," he was quoted as saying.
"There was a surge of Liverpool fans who had been drinking and that is what caused the disaster. The only thing different we did was put it under the headline 'The Truth'.
"I went on The World at One the next day and apologised. I only did that because Rupert Murdoch told me to. I wasn't sorry then and I'm not sorry now because we told the truth."
However, last year MacKenzie admitted that he did regret the paper's coverage of the disaster.