Alongside rights to a range of movies, the new multi-year deal extends carriage agreements for NBCU channels on Sky, including the Universal Channel, Syfy and Movies 24.
The content deal, which follows a similar recent agreement between Sky and Warner Bros, will give satellite pay-TV customers exclusive subscription window access to NBCUniversal movies after they have ended their run in UK cinemas.
Sky Movies will be the first subscription service in the UK and Ireland to show Snow White & the Huntsman, Battleship, Ted, The Bourne Legacy, ParaNorman and Savages.
Upcoming releases also covered in the deal include Anna Karenina, Les Miserables, The Man With The Iron Fists, Despicable Me 2 and About Time.
The movies will all be available on the 11 Sky Movies channels, in high definition and 3D where available, along with on-demand and on multiplatform service Sky Go.
Sky will also get access to a range of classic NBCUniversal titles, including Jurassic Park, Back to the Future and the American Pie series of films, as well as Mamma Mia, Gladiator and Scarface.
Sky Movies customers on Virgin Media, UPC and TalkTalk will also get access to the movies, and they will be made available to customers of the NOW TV internet television service.
"We are delighted to be able to announce an extension of our long-standing relationship with NBCUniversal," said Sky Movies director Ian Lewis.
"The combination of NBCU's hit movies with Sky's innovation will give customers an unrivalled in-home movies experience.
"Whether it's The Bourne Legacy on demand, Despicable Me in 3D, or Ted on the go, Sky Movies customers will enjoy the biggest and best selection of movies on their terms - and at least a year ahead of any other subscription service."
Alongside the content agreement, Sky has agreed a wide-ranging new channel carriage deal with NBCU. This covers the Universal Channel, home to shows such as Rookie Blue, Law & Order: Special Victims Unit and Cold Case; along with Keeping up with the Kardashians broadcaster E! Entertainment Television; and Syfy, known for Continuum, Warehouse 13 and Haven.
Sky viewers will also continue to enjoy The Style Network and Movies 24. Sky Media, Sky's advertising and sponsorship sales house, will continue to represent NBCU's channels.
Sky's director of operations and channels Jon Simkin said: "With a growing portfolio of popular shows from established pay TV brands including Universal Channel, E! Entertainment and Syfy, we are investing in more choice and quality for customers.
"At the same time, we are helping NBCU reach advertisers and sponsors through the on-going relationship with Sky Media."
NBCU president Belinda Menendez added: "We are very proud of the NBCUniversal portfolio of titles and channels represented by these two separate agreements.
"Sky customers will now have access to hit films such as Snow White and the Huntsman, The Bourne Legacy and Ted, in addition to a broad range of high-caliber programming on our bouquet of branded channels."