Former MotoGP presenter Perry takes over as BBC F1 lead anchor from Jake Humphrey, who has left the corporation to join BT Sport.
Eddie Jordan remains with the BBC as chief analyst, and Ben Edwards once again leads the television commentary with ex-F1 driver David Coulthard.
Lee McKenzie heads the pit lane team for television, but she will now be backed by F1 journalist Tom Clarkson, who joins the BBC as a pit lane reporter. Gary Anderson returns as technical analyst across television, radio and online coverage.
On Radio 5 Live, James Allen will once more act as correspondent and commentator, with Jennie Gow as pit lane reporter.
Former F1 driver Allan McNish will appear on Radio 5 Live for at least six Grands Prix this season as an expert analyst, starting in Barcelona.
There will be approximately 40 extra hours of live Formula One coverage on BBC network television this year, with practice sessions to be shown live at weekends on BBC Two and the new BBC Two HD channel.
BBC One and BBC One HD will show nine live races in 2013 - including Canada, Spain, Britain and Brazil - along with extended highlights of the races shown exclusively live on Sky.
"Everyone on the BBC team is hugely excited about the new season," said Ben Gallop, the BBC's Head of Formula 1.
"Last year saw us rise to the challenge of bringing the action to fans through the mix of live television and highlights, delivering great programmes which were reflected in impressive audience figures."
He added: "2013 sees new faces, practice on BBC Two and HD on live race weekends and a greater sharing of talent across BBC television, radio and online.
"With Suzi Perry at the helm, we're aiming to bring even more content, insight and access to audiences throughout the season."
Alongside TV and radio, the BBC is also offering extensive online coverage of F1 via the BBC Sport website and apps.
Web users can access live simulcasts of the BBC's live races, including additional options such as the 'driver tracker', on-board cameras and the pit lane stream.
Motorsport legend Murray Walker will provide a series of archive-based videos for every race of the season under the Murray's Memories strand.