Carla Gugino is in final talks to star alongside Ben Stiller in comedy Night at the Museum, The Hollywood Reporter reveals.

Directed by Shawn Levy (Cheaper by the Dozen), the live-action/CGI feature will focus on a museum security guard (Stiller) who accidentally sets off an ancient curse causing the animals and insects on display to come to life.

The picture is due to begin filming in Vancouver next month with a view to a holiday release this year.

Gugino (Spy Kids) can next be seen in supernatural thriller Rise, starring Lucy Liu and Michael Chiklis.