
The Dr Seuss adaptation, which features the voices of Jim Carrey and Steve Carell, is also number one in the US.
The top ten features six new entries, with The Spiderwick Chronicles, Step Up 2 the Streets and Meet the Spartans and last week's number one 10,000 B.C. making up the top five.
The top ten in full:
1. (-) Horton Hears A Who! - £2,952,000
2. (-) The Spiderwick Chronicles - £2,560,000
3. (-) Step Up 2 the Streets - £2,362,000
4. (-) Meet the Spartans - £1,141,900
5. (1) 10,000 B.C. - £1,035,130
6. (2) Vantage Point - £742,510
7. (3) The Game Plan - £563,000
8. (4) The Other Boleyn Girl - £484,230
9. (-) Race - £367,970
10. (-) The Orphanage - £329,530
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