The choice of former YBA Sam Taylor-Johnson to direct the film is an inspired one - she already has experience of dealing with fan expectations, having told the story of the young John Lennon in Nowhere Boy.
> Fifty Shades of Grey: Digital Spy casts the erotic fiction bestseller
With a credible name behind the camera, big name actors should be less scared of jumping into the project, and if the bookmakers are to be believed, it's still a very open field.
Paddy Power rate Alexis Bledel as the favourite to play Ana, at just 5/1. At 10/1 are Amanda Seyfried, Emilia Clarke, Felicity Jones and ex-porn star Sasha Grey.
A hilarious spokesperson for the bookmaker said: "We've seen a ton of money on Alexis Bledel and it's clear punters fancy her for the role - we'll be facing a spanking payout if she's tied down for the role."
William Hill are also big fans of Bledel, offering odds as short as 2/1 for the former Gilmore Girls star.
"Alexis has not been averse to flashing a bit of flesh in Mad Men and ultimately, that will be a prerequisite to playing Ms Steele," said the company's spokesman Joe Crilly, behind steamed-up spectacles we assume.
"She also has the acting clout to star in what will be the biggest book adaptation since the Harry Potter films."
Speaking of Potter, William Hill offers relatively mean odds of 6/1 for Emma Watson to take the role of Ana, this despite her pointing out how ridiculous the idea is.
For having the temerity to bite her thumb at the role, the Bling Ring actress and English undergrad is unkindly (and inexplicably) dismissed as "Emma 'Prude' Watson" by Paddy Power and given odds of 25/1 - the same as Jennifer Lawrence, Selena Gomez and Olivia Wilde.
Another actress to rule herself out is Mila Kunis, but that hasn't stopped Paddy Power rating her as 12/1, William Hill making her second favourite at 9/2 and Ladbrokes inexplicably making her their favourite at 3/1
When it comes to Christian Grey, the bookies (for some reason) haven't been as noisy in trumpeting their odds recently.
Ladbrokes makes The Vampire Diaries star Ian Somerhalder its 4/1 favourite, suggesting that he and Kunis are getting some serious money behind them.
"Somerhalder and Kunis would be the dream line up as far as punters are concerned," claimed Jessica Bridge.
"With Taylor-Wood directing it's sure to attract Hollywood's A-listers to the role."
Past Ian, you're looking at Ryan Gosling at 5/1, Cilian Murphy at 6/1 and Matt Bomer at 7/1.
Do you think the bookmakers are on the right track with their latest odds? Let us know your thoughts in the comments box below.