Speaking to Digital Spy, Biggs admitted that he is most proud of his character Jim Levenstein's sexual encounter with a pie in the first American Pie movie.
"I'm proud of all the [American Pie] movies and, really, all the performances," he said. "I like the pie scene because I think back on that, and I know that in order for that scene and, in a way, that whole movie to work... it required for me to absolutely go for it in that scene.
"[I had to] put all inhibition aside and have no fears and just go for it - probably because I was just young and naive! I'm really proud of the pie scene. It's become this iconic scene and I'm proud that I'm a part of it."
Asked if he would consider returning for a fifth American Pie theatrical movie, Biggs said: "There's always the possibility, I suppose.
"For me personally, if the script is good and it's the right filmmakers, if Jon [Hurwitz] and Hayden [Schlossberg] come back, and the cast. If all the things are in place, it would be hard for me to pass up an opportunity to work with my friends again.
"I love working with these people and I love playing Jim."
Discussing a potential plot for the next movie, Biggs joked: "We could do a prequel and I could play Jim's Dad. I just need to get eyebrow implants or something!"
American Pie: Reunion is out of DVD and Blu-ray with Ultraviolet digital copy now.