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Other stars lined up for the project include Bill Nighy, Nathan Lane and Eugene Levy.
British actor Freddie Highmore was confirmed for the title role earlier this year.
The movie, which revolves around the story of a young robot created to replace a scientist's son, is being helmed by David Bowers. It is scheduled for released in 2009.
The original Astro Boy was created in the 1950s by manga pioneer Osamu Tezuka.
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