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The actress, whose new film How To Lose Friends And Alienate People is released on Friday, spoke to MTV about her future in the franchise.
"I'm in," she confirmed. "I'm not saying anything, I know there's rumours..."
Spider-Man director Sam Raimi and star Tobey Maguire recently closed a deal to make Spider-Man 4 and Spider-Man 5 back-to-back.
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