The actor has been tapped to take on the role of screenwriter David Sumner, originally played by Dustin Hoffman, in the story about a couple who find their marriage crumbling after relocating to the deep South, eventually leading to a violent showdown with the locals.
Rod Lurie will write and direct the project, while Marc Frydman will produce alongside Lurie under their Battleplan Productions banner. Screen Gems's Gilbert Dumontet will executive produce.
Filming on the project is slated to begin in August.
Marsden has previously appeared in 27 Dresses, Enchanted, Hairspray and as Cyclops in the X-Men franchise.