Movies
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According to Contactmusic, the country's National Film Board decided that the movie's raunchy content was in violation of Thailand's "moral principles".
Vira Rojpojchanarat, the Culture Ministry Permanent Secretary, added that officials were worried that the film "may encourage copycats here".
An appeal by distributors M Pictures against the decision has been dismissed.
Zack And Miri, which was directed by Kevin Smith, follows two flatmates who decide to make their own porn movie in order to solve their financial problems.
Last year, cinema bosses at Megaplex Theatres in Utah refused to screen the film, suggesting that it was too crude for their customers.
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