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Based on the 1978 original, the movie revolves around a batch of flesh-eating fish who are accidentally released into the river of a small town.
The actress, who plays Vanessa Abrams in the CW show, will take on the part of Kelly, a local girl who befriends a group of college students who have arrived in the area for spring break.
She joins previously announced cast members Elisabeth Shue, Adam Scott and Richard Dreyfuss, who will make a cameo appearance in homage to his role in Jaws.
Production on Piranha 3-D begins later this month, with a slated release date of March 19, 2010.
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