The screenwriter told the New York Post in June that he was having writer's block and trying to figure out "a Sid-less scenario", referring to penning a sequel without franchise heroine Sidney Prescott (Campbell).
Courteney Cox and David Arquette have confirmed that they will return to the series, but Williamson indicated that Campbell's character may have met an untimely end in the ten-year span between movies.
He told MTV: "It’s gonna sort of involve our returning characters - the only characters left alive. We’ve got Courteney Cox and David Arquette returning."
Williamson confirmed that the film will be a direct sequel to the events in the first trilogy, adding: "[The movie] picks up after Scream 3 - ten years later."
Director Wes Craven recently told DS that he would consider directing the new instalment.