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He had been quoted as saying that his role in Harry Brown would be his last as a lead character, The Mirror reports.
However, the 76-year-old insisted that his words had been misinterpreted and said that he was still open to offers.
Asked if the reports of his retirement were true, Caine replied: "No, no, no. I didn't say that. You know you get misquoted all the time.
"The guy said to me, 'You gonna retire?' I said, 'You don't retire in this business, the business retires you'."
However, he admitted that he was more selective of roles now.
Caine also said that when he did retire, there would be "no big announcement".
Harry Brown, about an elderly ex-serviceman's attempt to avenge his best friend's murder, will be released in UK cinemas on November 13.
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