The movie, which will see Will Ferrell re-teaming with director Adam McKay (Anchorman, Talladega Nights, Step Brothers), is scheduled for release in August 2010.
Johnson and Jackson will play two elite cops who are envied by two desk officers, played by Ferrell and Mark Wahlbeg. Steve Coogan will play the villain.
Earlier this month, Eva Mendes, Michael Keaton and Damon Wayans Jr were also confirmed for the project.
Previously titled The B Team, McKay and writer Chris Henchy switched the title to avoid confusion with the upcoming A-Team movie.