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The Twilight Saga: New Moon co-stars lock lips in the rock 'n' roll biopic, which stars Fanning as Cherie Currie and Stewart as Joan Jett.
According to Just Jared, Fanning told V magazine: "[The kiss is] passionate, they were just as close as two could get.
"[The drugs are] actually crushed B vitamins. Kristen and I were, like, our hair is gonna grow a lot from these."
Fanning said that she "really enjoyed" making the movie "because it really happened, it's not just a made-up story about a 15-year-old running wild".
She added: "It's a true story of her evolution from good Valley Girl to bad rock 'n' roll princess."
The Runaways opens later this year.
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