Speaking to Film24, the 50-year-old said that director Quentin Tarantino always meant for the franchise to be a trilogy.
The Splash star also revealed that she would be game to reprise her role of Elle Driver, who was presumably blinded and left for dead in Kill Bill: Vol. 2.
"Think about it. There's always been a tradition of blind samurai, and you never actually saw [my character] expire in the other film," she said.
Uma Thurman recently admitted that she is keen to begin training for the upcoming third Kill Bill instalment.
Last October, Tarantino confirmed that the follow-up will be out in cinemas in 2014.