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The 47-year-old starred as the Marvel Comics hero in director Stephen Norrington's 1998 movie Blade and its two sequels, Blade II and Blade Trinity.
Speaking to Arrow in the Head, Snipes claimed that he would consider appearing in a fourth Blade instalment "if the script was right".
Last summer, Norrington confirmed that he was working on a Blade prequel with Stephen Dorff.
Snipes co-stars in crime drama Brooklyn's Finest, due to hit theatres on March 5.
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