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The project, from Gattaca writer-director Andrew Niccol, centres on a society where ageing stops at 25 and those wishing to live longer must buy and bank extra time to continue their life.
Inception star Murphy will play an operative who works for the Timekeepers, an organisation tracking a man (Timberlake) who inherits a fortune and goes on the run with an heiress (Seyfried).
I'm.mortal will begin production in September.
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