The actress, who plays a sex-obsessed dentist, said that she fell into the role a lot easier then she thought she would.
She explained to USA Today: "The crazy part is the ease with which all these words are falling out of my mouth. I don't know what I've unlocked here."
Aniston also revealed that she felt awkward taking off her clothes in front of actor Charlie Day.
She added: "It's so funny and weird and twisted. I'm naked with Charlie Day, who I've known for minutes."