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According to The Hollywood Reporter, Khan is in discussions to star as villain Van Atter alongside Andrew Garfield and Campbell Scott in the Columbia production.
Marc Webb’s reboot of the Spider-Man franchise began production this month in Los Angeles with casting decisions reportedly close to finalisation.
Khan would be the second Slumdog Millionaire star to be cast as a villain in a Hollywood movie after his co-star Anil Kapoor was snared for the new Mission: Impossible instalment.
Khan has already been a part of several Hollywood productions, including The Namesake and A Mighty Heart.
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