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The sci-fi horror, based on Capcom's hit video game series, will be released on September 14, 2012 through Sony's Screen Gems. The date lines up the untitled fifth film's opening with the previous three franchise instalments, which also had September debuts.
Milla Jovovich will reprise her role as Alice in Resident Evil 5.
Last year's Resident Evil: Afterlife, the series' first in 3D, took in $290 million at the worldwide box office. The franchise has grossed more than $660 million at the box office in total.
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