The new movie sees Magneto and Professor X meeting in the 1960s against the backdrop of the Cold War.
Speaking to Hitflix, Vaughn said: "There were two main influences I had. First, I watched all the early Bond movies again.
"You Only Live Twice, I watched a couple of times. I really wanted it to feel like a '60s Bond film, but with a little bit of reality it could be grounded in."
He also teased a follow-up to the movie that could open with the assassination of John F.Kennedy, who has been shot with a "magic bullet controlled by Magneto".
The helmer said last month that he was keen on making a sequel to the film which will see Magneto and Professor X in the late 1960s, the era of flower power.
Watch the international trailer for X-Men: First Class below: