The producer spoke out on his struggle to develop the dark comedy, stating that he believes the film was worth the effort, according to The Hollywood Reporter.
"In this day and age, you need a lot of patience if you are in the movie business," Ratner said. "But I think it's been well worth the wait. From the beginning, I knew it was a great concept."
Horrible Bosses was first sold to the film studio New Line in 2005. Actors including Ashton Kutcher, Ryan Reynolds, Philip Seymour Hoffman and Johnny Knoxville were all attached to star in the movie at some point before a cast was eventually assembled.
Ultimately, Jason Bateman, Jason Sudeikis, Charlie Day, Kevin Spacey, Jennifer Aniston, Colin Farrell and Jamie Foxx signed on for the film.
Aniston recently revealed that she was thrilled by the opportunity to play the role of sexy dentist Julia in Horrible Bosses, confessing that she is not often offered such juicy parts.
Meanwhile, Day has said that he found the more provocative scenes opposite Aniston to be awkward, claiming that it was particularly difficult to shoot the scene in which he was required to pretend to be drugged while allowing Aniston to straddle him.
Watch the trailer for Horrible Bosses below: