The Paul star confessed that if it were up to her, she would be thrilled to reprise her role as Ellen Ripley.
"I could definitely kick that alien's ass again," Weaver told Moviefone. "While I can't speak for them, I think for Fox [the studio behind the film], once you're 60, you're not going to be starring in an action movie."
She continued: "I think it's too bad that that's the case. I would have liked to do one last story where we go back to the planet, where Ripley's history is resolved. But I do feel like her story is unfinished."
In April, Weaver revealed that she thinks extra-terrestrials exist and that the US government are covering up the truth about alien visitations.
Last year, the 61-year-old expressed interest in working with director Ridley Scott on the Alien prequel that ultimately became Prometheus.
Weaver can be seen next in Abduction opposite Twilight star Taylor Lautner.
Watch the trailer for Abduction below: