The political drama will open the 68th Venice Film Festival and stars Clooney as a governor with his eyes on the White House. Ryan Gosling also stars as his spokesman who gets drawn into political corruption.
Co-stars Marisa Tomei, Evan Rachel Wood, Philip Seymour Hoffman and Paul Giamatti were also in attendance for Clooney's fourth film as a director.
Madonna's new movie W.E. and Roman Polanski's Carnage will also debut at the 2011 Venice Film Festival.
> Ryan Gosling: 'George Clooney is like Michael Jackson'
Take a look through Digital Spy's Ides of March premiere picture gallery below: