The actress admitted that she hasn't heard anything about a fourth instalment, but claimed that there is always a chance the Fockers could return to the big screen.
"I have no idea, [but] anything is possible. People never tire of the Fockers," she joked to Parade.
Danner went on to reveal that she loves working with her Meet the Parents co-stars Robert De Niro, Ben Stiller and Owen Wilson.
"I just stand there and learn from all of them. I laugh so hard," she said. "Bob is great, he's so relaxed. He's wonderful just to watch work. I don't think there's anybody who works in a more relaxed manner than he does."
Danner stars with Anna Faris and Chris Evans in the comedy What's Your Number?, which opens on September 30 in the US and the UK.
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Watch a trailer for What's Your Number? below: