The Last Night actress will appear in Leos Carax's new movie alongside Kylie Minogue, reports Allocine.
The film stars Dennis Levant as a man who travels between different versions of his life, which see him cast as a murderer, beggar, CEO, monstrous creature and family man.
The cast, which also includes Jean-François Balmer, play different roles in each version of the lead's life.
Rumours that Juliette Binoche would also appear in the movie were later quashed.
Carax is best known for his work on Pola X, Mauvais Sang and his contribution to the Tokyo! omnibus.
Mendes has recently been connected to Drive star Ryan Gosling.