Deadline reports that Walden Media has acquired the rights to adapt the property, which is being developed with a view to have Lopez star in the titular role.
At present, Lopez is only confirmed to be involved off-screen as she will produce through her Nuyorican Productions banner.
"When the ACME agency's greatest detective Carmen Sandiego becomes the world's greatest thief, it's up to her former partner to follow her clues and track her down," the film's tagline reads. "Their cat and mouse game leads the partner to confront a greater mystery: is Carmen really a thief or a hero?"
PBS aired three different animated Carmen Sandiego series between 1991 and 1999.
Lopez recently finished filming romantic comedy What to Expect When You're Expecting with Cameron Diaz.
Listen to the original Where in the World is Carmen Sandiego? theme tune below:
> Jennifer Lopez: "I'm tougher now on American Idol"
> Jennifer Lopez working on new MTV show