Brian Robins is directing the comedy, which also features Clark Duke, Allison Janney, Kerry Washington and Jordan-Claire Green.
The movie stars Murphy as fast-talking literary agent Jack McCall, who will say anything to get what he wants.
When he angers a New Age guru, he finds his life linked to a Bohdi tree.
Every time he says a word the tree loses a leaf, forcing him to find creative ways of not speaking in order to save the lives of the tree and himself.
Murphy recently stepped down as the host of the 2012 Academy Awards following the departure of Oscars and Tower Heist producer Brett Ratner.
It was confirmed on Thursday night that Billy Crystal will take over as Oscars host.
> Oscars 2012: Who should replace Eddie Murphy as Academy Awards host?
> Oscars 2012: How Eddie Murphy, Brett Ratner lost the Academy Awards