The Zoolander star will take the stage at the 2012 Academy Awards, telecast producers Brian Grazer and Don Mischer announced on Thursday (February 16).
Stiller joins previously announced presenters including Emma Stone, Angelina Jolie, Bradley Cooper, Cameron Diaz and Tom Hanks.
It was confirmed yesterday that Stiller's Madagascar 3: Europe's Most Wanted co-star Chris Rock will make his return to the ceremony as a presenter. Rock previously hosted the awards show in 2005.
Stiller can next be seen in Neighbourhood Watch. He will also direct and star in The Secret Life of Walter Mitty.
The 84th Academy Awards will air on February 26 on ABC in the US and on Sky Movies in the UK.
Watch the trailer to Madagascar 3: Europe's Most Wanted below: