Since achieving worldwide fame after playing an arrogant senior fashion assistant in The Devil Wears Prada, Blunt has starred in numerous films including The Young Victoria, Gnomeo & Juliet, The Adjustment Bureau and Salmon Fishing in the Yemen.
When asked if she would ever star in a superhero movie, Blunt - who was considered for Iron Man 2 and Captain America - told New York Magazine: "Usually the female parts in a superhero film feel thankless - she's the pill girlfriend while the guys are whizzing around saving the world.
"I didn't do the other ones because the part wasn't very good or the timing wasn't right, but I'm open to any kind of genre if the part is great and fun and different and a challenge in some way. I would love to do a comic-book movie or a science-fiction film that would scare the bejesus out of me.
"Maybe I need to be James Bond! I just did Looper, because it's so original and breathtakingly cool. The time-travel aspect is just a backdrop to visit this heightened world, where you're atoning for something and attempting to be more than you've been."
Blunt can be seen next in The Five-Year Engagement, which opens the Tribeca Film Festival on April 18 prior to its theatrical release date on April 27 in the US and June 22 in the UK.
Watch the trailer for The Five-Year Engagement below: