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The Pirates of the Caribbean actress would play Katie in the highly-anticipated movie, according to Twitch Film.
Safe Haven centres on a haunted young woman who moves to the small town of Southport, North Carolina in order to escape the secrets of her past.
There, she meets two people - the widowed store owner Alex and her single neighbour Jo - who will change her life forever.
Knightley can next be seen in the apocalyptic comedy Seeking a Friend for the End of the World.
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Watch the trailer for Seeking a Friend for the End of the World below:
