The studio boss commented on the technology and several other aspects of the film industry during a conference held at UCLA on Friday (April 6), according to The Hollywood Reporter.
Meyer said: "I'm not a fan of 3D as an audience member. I'm too old for it. I don't like wearing the glasses over my glasses.
"There is a place for it, an important place. I just don't think we should kid ourselves that it is an end-all for the business."
Universal recently released The Lorax in 3D in the US, achieving box office figures that Meyer said were more than twice what the studio had anticipated.
He said that there are no current plans for a sequel, but admitted: "It does have us thinking about doing more Dr Seuss movies."
Meyer also addressed his much-publicised attack on his own studio last year, during which he commented that Universal "make a lot of s**tty movies" and singled out Cowboys and Aliens, The Wolfman and Scott Pilgrim vs. The World.
At the conference, Meyer said of his remarks: "What I said is, we make some good movies and some s**tty movies. Nobody ever sets out to make a s**tty movie."
The Lorax will open in the UK on July 27.
Watch a trailer for the film below: