The psychological drama, formerly titled Womb, is to open in cinemas on May 4 ahead of its DVD and Blu-ray bow on May 7 through Arrow Films. The Sci-Fi-London Film Festival will host a special advance preview on May 1.
Clone sees Smith play Tommy, a man whose romance with Rebecca (Casino Royale's Eva Green) is cut short when he is killed in a car accident. In a world where cloning is widely used, Rebecca decides to take drastic action by conceiving and giving birth to his genetic copy.
Benedek Fliegauf directed Clone, which features Lesley Manville and Skins's Hannah Murray in its supporting cast.
Clone featured among the lineup at the 2010 BFI London Film Festival.
Photo gallery - Matt Smith and Eva Green in Womb: