The Star Trek actor described the project based on the EL James book as "interesting" and insisted that he wouldn't say no to playing the titular protagonist.
"I do know about Fifty Shades of Grey because Alice Eve, who's in [the Star Trek sequel], has been reading it like crazy, so yeah, I've heard about it," Pine told Access Hollywood.
"It'd be a hell of a choice for me, I think. It sounds like an interesting film."
In the same interview, Pine described the tone of the Star Trek follow-up as "relentless", saying that the film is as action-packed as the original.
Vampire Diaries star Ian Somerhalder has also expressed an interest in portraying Christian Grey.