The movie's staggering $200 million bow comes almost ten years to the day since Tobey Maguire's Spider-Man became the first blockbuster to cross the $100 million mark on its Stateside opening.
Ironically, the two highest-grossing films of all time - James Cameron's Avatar and Titanic - are not among the top 20 biggest opening weekends. Digital Spy takes a look at the biggest box office debuts below...
> 'The Avengers' complete coverage
> 'The Avengers' video site
Photo gallery - Top 20 box office record breakers: