Depp can currently be seen in Dark Shadows, in which he plays Barnabas Collins, who was turned into a vampire after breaking the heart of a witch.
The 48-year-old actor is one of the many stars to have portrayed vampires on the big screen recently, but said that he isn't worried by his contemporaries, including Twilight's Robert Pattinson.
"There's room for two vampires on this block - as long as he remembers I am the Alpha Vampire," Depp told Us Weekly.
Depp also admitted that he loved his character's wardrobe so much that he may have kept some of his items of clothing for himself.
"Yeah, a few fell off the truck for sure," he quipped.
Watch the trailer for Dark Shadows below: